Hojun Li, M.D., Ph.D.

Principal Investigator

Moores Cancer Center, Office 5344

hojun@health.ucsd.edu

Endowed Assistant Professor of Pediatrics

University of California, San Diego (2024 - present)

Charles W.(1955) and Jennifer C. Johnson Clinical Investigator

Koch Institute for Cancer Research, Massachusetts Institute of Technology (2019 - 2023)

Postdoctoral Fellow

Whitehead Institute for Biomedical Research (2016 - 2019)

M.D., Ph.D. in Cell and Molecular Biology

University of Pennsylvania Perelman School of Medicine (2005 - 2012)

B.S. in Biochemistry

University of Maryland, College Park (2001 - 2005) …Go Terps!

Hojun trained in the M.D./Ph.D. program at the University of Pennsylvania, performing his graduate thesis with Kathy High quantifying the insertional mutagenesis risk of AAV vectors and developing the first methodology for in vivo genome editing. He performed Pediatrics Residency at Boston Children’s Hospital/Boston Medical Center and Hematology/Oncology Fellowship at Dana-Farber Cancer Institute/Boston Children’s Hospital. Following clinical training Hojun was a postdoctoral fellow with Harvey Lodish at the Whitehead Institute elucidating the cellular developmental mechanism of enhanced red cell production by glucocorticoids, and then established his independent lab at the MIT Koch Institute as the Charles W.(1955) and Jennifer C. Johnson Clinical Investigator. During his time as a postdoc and independent fellow Hojun attended on the Pediatric Stem Cell Transplant services at Boston Children’s  and Dana-Farber. He has been an American Society of Hematology Scholar, March of Dimes Basil O’Connor Award Scholar, Hartwell Individual Biomedical Research Awardee, DBA Foundation Matthew Vroman Building Hope for the Future Awardee, Hyundai Hope on Wheels Hope Scholar, a Department of Defense Career Development Independent Fellow, and an NIH Clinical Investigator (K08) Fellow, and has won teaching awards both as a resident and as an attending. In 2024, Hojun and the lab moved to the Department of Pediatrics at the University of California, San Diego and Moores Cancer Center, where Hojun now also attends on the Bone Marrow Transplant service at Rady Children’s Hospital.

Meet the Team

  • Thach Pham, Ph.D.

    Postdoctoral Fellow

    Project: Functional genomics of erythroid progenitor and stem cell biology in primary cell systems

  • Sara Bear, M.D.

    Pediatric Hematology/Oncology Fellow

    Project: Stem cell graft lineage functionality

  • Nick Chan, B.S.

    BISB Graduate Student

    Project: Kinetics and clonality of stem cell transplant engraftment

  • Parker Côté, B.S.

    BISB Graduate Student

    Project: Application of single cell genomics to human blood physiology

  • Brittany Crown, B.S.

    BMS Graduate Student

    Project: Mechanisms of hematopoietic stem cell engraftment

  • Rylee Start, B.S.

    (Picture coming soon)

    BMS Graduate Student

    Project: Pseudotemporal dynamics of developmental gene expression

  • Thomas Uhler, B.S.

    Medical Student Researcher (Joint w/ Bui lab)

    Project: Nomination of myeloid-biased stem cell markers

  • Ambika Venkatakrishnan, B.S.

    (Picture coming soon)

    Masters student

    Project: Normalization of pseudotemporal erythroid trajectories

  • Alina Luchyshyn, B.A.

    Research Associate

    Project: Epigenetic control of erythroid progenitor cell proliferation

  • Hannah Chae, B.S.

    Research Associate

    Project: Point-of-care molecular genetic testing

  • Suchit Bhayani

    Undergraduate Researcher

    Project: Machine learning of hematopoietic single cell data

  • John Bolibol

    Undergraduate Researcher

    Project: Hematopoietic-targeting CRISPR design and validation

  • Albert Ho

    Undergraduate Researcher

    Project: Single cell gene expression state changes following stem cell transplantation

  • Lauraine Kong

    Undergraduate Researcher

    Project: Multi-omic profiling of age-specific human hematopoiesis

  • Siya Maheshwari

    Undergraduate Researcher

    Project: Hematopoietic-targeting CRISPR design and validation

  • Jose Rodriguez

    Undergraduate Researcher

    Project: Mechanisms of glucocorticoid-mediated erythroid proliferation

  • AJ Youssef

    Undergraduate Researcher

    Project: Genetic mediators of erythroid developmental transitions

Join us!

We are always looking for highly motivated colleagues that love to do science in a fun and collaborative environment. Please get in touch with Hojun (email address above) if you are interested in coming aboard!

Alumni

We couldn’t be more proud of those for which we have had the privilege of being part of their training journey.

Technicians

Jideofor Ezike, completed Ph.D. at MIT

Zoë Feder, now graduate student at Harvard

Guinevere Connelly, now graduate student at Duke

Tatum Braun, now medical student at Tufts

Orville “Kirky” Kirkland Jr., now graduate student at Harvard

Ngoc “June” Hoang, now medical student at Drexel

Leah Hirsch, now graduate student at Yale

Alicia Meshulam, currently at UCSF

Undergraduates

Swanny Lamboy-Rodriguez, completed Ph.D. at MIT, now scientist at Aleksia Therapeutics

Sharon Onggo, now graduate student at Johns Hopkins

Christine Goglia, now graduate student at Harvard

Wilson Gomarga, now graduate student at Harvard

Yenthanh Le, now medical student at SUNY Stony Brook

Hoang Dinh, now graduate student at UPenn

Michael Kuoch, completed M.Eng. in the lab, now at Citadel, LLC

Erin Thompson, now research associate at Scripps Institute of Oceanography

Amelia Seabold, completed concurrent M.S. in the lab, now graduate student at Oxford

Stuti Khandwala, now MD/PhD student at Yale

See Yeon “Nicole” Ryu, now research associate at Vivtex

Lily Mai, completed undergraduate training at Harvard, now research associate at Boston Children’s Hospital

Alice Lam, completed concurrent M.Eng. in the lab, now graduate student at Stanford

Aaron Bhattachan, completing undergraduate training at Northeastern

Kate Lu, now MD/PhD student at Cornell/MSK/Rockefeller Tri-Institutional Program

Charles Choi, now computational biologist in Korea

Aidan Arnaldo, now analyst at Larry Walker & Associates

Rotation Students

Avery Williams (BMS graduate group), now graduate student in Fisch lab at UCSD

Anushka Poola (BMS graduate group), now graduate student in Antal lab at UCSD